LifeMD vs SkyRx: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
Quick Verdict
LifeMD has the higher ClearScore (76 vs 75)
LifeMD is more affordable ($189/mo vs $299/mo)
SkyRx has higher ratings (4.4/5 vs 4.3/5)
LifeMD scores better on value (4.2/5 vs 3.6/5)
LifeMD
$189/mo
starting price
Board-certified doctors prescribing GLP-1s with both compounded and brand-name options. Known for responsive customer service.
SkyRx
$299/mo
starting price
Premium GLP-1 program with full labs, high-touch clinician access, and both semaglutide and tirzepatide.
LifeMD vs SkyRx: Full Comparison
| LifeMD | SkyRx | |
|---|---|---|
| ClearScore | 76/100 ✓ | 75/100 |
| Overall Rating | 4.3/5 | 4.4/5 ✓ |
| Review Count | 165 ✓ | 58 |
| Starting Price | $189/mo ✓ | $299/mo |
| Medications | Compounded Semaglutide, Compounded Tirzepatide | Compounded Semaglutide, Compounded Tirzepatide |
| Telehealth | Yes | Yes |
| Insurance | Not accepted | Not accepted |
| HSA/FSA | Accepted | Accepted |
| Founded | 2020 | 2022 |
| States Served | All 50 states | All 50 states |
Programs & Pricing
LifeMD Programs
GLP-1 Weight Management
$189/mo
Medications: Compounded Semaglutide, Compounded Tirzepatide
- Medication
- Board Certified Doctor
- Ongoing Monitoring
- Free Shipping
SkyRx Programs
Premium Weight Loss
$299/mo
Medications: Compounded Semaglutide, Compounded Tirzepatide
- Medication
- Full Labs
- Dedicated Clinician
- Priority Support
Ratings Breakdown
| Category | LifeMD | SkyRx |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
LifeMD edges out SkyRx with a ClearScore of 76 vs 75. LifeMD is more affordable starting at $189/mo compared to $299/mo. For customer support, SkyRx rates higher (4.8/5). The best choice depends on your priorities, medication preferences, and budget.