Mayo Clinic Diet vs Medi-Weightloss: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
Quick Verdict
Mayo Clinic Diet has the higher ClearScore (78 vs 74)
Mayo Clinic Diet is more affordable ($50/mo vs $399/mo)
Mayo Clinic Diet has higher ratings (4.4/5 vs 4.2/5)
Mayo Clinic Diet scores better on value (3.8/5 vs 3.5/5)
Mayo Clinic Diet
$50/mo
starting price
World-renowned Mayo Clinic's evidence-based weight loss program now includes GLP-1 prescribing with specialized meal plans for medication users.
Medi-Weightloss
$399/mo
starting price
National franchise with 100+ clinics offering physician-supervised GLP-1 programs, nutrition counseling, and metabolic testing.
Mayo Clinic Diet vs Medi-Weightloss: Full Comparison
| Mayo Clinic Diet | Medi-Weightloss | |
|---|---|---|
| ClearScore | 78/100 ✓ | 74/100 |
| Overall Rating | 4.4/5 ✓ | 4.2/5 |
| Review Count | 98 | 342 ✓ |
| Starting Price | $50/mo ✓ | $399/mo |
| Medications | Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide ✓ | Branded Semaglutide, Branded Tirzepatide |
| Telehealth | Yes | Yes |
| Insurance | Not accepted | Accepted |
| HSA/FSA | Accepted | Accepted |
| Founded | 1889 | 2007 |
| States Served | All 50 states | 19 states |
Programs & Pricing
Mayo Clinic Diet Programs
Companion Subscription
$49.99/mo (diet support only)
- Mayo Clinic Diet Program
- Glp1 Meal Plan
- Nutrition Guidance
Clinical Subscription
$99.99/mo + $99.99 start fee + medication
Medications: Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide
- Clinician Visits Via Amwell
- Mayo Clinic Diet Program
- Glp1 Meal Plan
- Nutrition Guidance
- Exercise Program
Medi-Weightloss Programs
Signature Program
$399/mo
Medications: Branded Semaglutide, Branded Tirzepatide
- Medication
- In Person Visits
- Nutrition Counseling
- Metabolic Testing
- Body Composition
Ratings Breakdown
| Category | Mayo Clinic Diet | Medi-Weightloss |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
Mayo Clinic Diet edges out Medi-Weightloss with a ClearScore of 78 vs 74. Mayo Clinic Diet is more affordable starting at $50/mo compared to $399/mo. For customer support, Medi-Weightloss rates higher (4.5/5). The best choice depends on your priorities, medication preferences, and budget.