Medi-Weightloss vs SkyRx: Prices, Programs & Reviews (2026)

Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.

Quick Verdict

SkyRx has the higher ClearScore (75 vs 74)

SkyRx is more affordable ($299/mo vs $399/mo)

SkyRx has higher ratings (4.4/5 vs 4.2/5)

SkyRx scores better on value (3.6/5 vs 3.5/5)

Medi-Weightloss logo

Medi-Weightloss

74
Good
4.2 (342 reviews)

$399/mo

starting price

National franchise with 100+ clinics offering physician-supervised GLP-1 programs, nutrition counseling, and metabolic testing.

100+ LocationsInsurance AcceptedComplete Program
Visit Medi-Weightloss
SkyRx logo

SkyRx

75
Very Good
4.4 (58 reviews)

$299/mo

starting price

Premium GLP-1 program with full labs, high-touch clinician access, and both semaglutide and tirzepatide.

PremiumFull LabsHigh-Touch
Visit SkyRx

Medi-Weightloss vs SkyRx: Full Comparison

Medi-Weightloss SkyRx
ClearScore 74/100 75/100
Overall Rating 4.2/5 4.4/5
Review Count 342 58
Starting Price $399/mo $299/mo
Medications Branded Semaglutide, Branded Tirzepatide Compounded Semaglutide, Compounded Tirzepatide
Telehealth Yes Yes
Insurance Accepted Not accepted
HSA/FSA Accepted Accepted
Founded 2007 2022
States Served 19 states All 50 states

Programs & Pricing

Medi-Weightloss Programs

Signature Program

$399/mo

Medications: Branded Semaglutide, Branded Tirzepatide

  • Medication
  • In Person Visits
  • Nutrition Counseling
  • Metabolic Testing
  • Body Composition
View All Medi-Weightloss Plans

SkyRx Programs

Premium Weight Loss

$299/mo

Medications: Compounded Semaglutide, Compounded Tirzepatide

  • Medication
  • Full Labs
  • Dedicated Clinician
  • Priority Support
View All SkyRx Plans

Ratings Breakdown

Category Medi-Weightloss SkyRx
Overall
4.2
4.4
Value
3.5
3.6
Ease of Use
3.9
4.3
Support
4.5
4.8
Medication Quality
4.6
4.6
Results
4.3
4.5

The Bottom Line

SkyRx edges out Medi-Weightloss with a ClearScore of 75 vs 74. SkyRx is more affordable starting at $299/mo compared to $399/mo. For customer support, SkyRx rates higher (4.8/5). The best choice depends on your priorities, medication preferences, and budget.

Frequently Asked Questions

Is Medi-Weightloss or SkyRx cheaper?
SkyRx starts at a lower price point ($299/mo vs $399/mo). However, pricing depends on the specific program and medication you choose, so compare each provider's program details carefully.
Which provider has better reviews, Medi-Weightloss or SkyRx?
SkyRx has a higher overall rating (4.4/5 vs 4.2/5). Medi-Weightloss has 342 reviews and SkyRx has 58 reviews. Both ratings and review volume matter when evaluating providers.
Do Medi-Weightloss and SkyRx offer the same medications?
Medi-Weightloss offers Branded Semaglutide, Branded Tirzepatide. SkyRx offers Compounded Semaglutide, Compounded Tirzepatide. Your prescriber will recommend the best medication based on your health profile, weight loss goals, and medical history.
Can I use insurance with Medi-Weightloss or SkyRx?
Medi-Weightloss accepts insurance. SkyRx does not currently accept insurance. For out-of-pocket costs, both providers accept HSA/FSA cards.

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