Sequence vs SkyRx: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
Quick Verdict
Sequence has the higher ClearScore (79 vs 75)
Sequence is more affordable ($99/mo vs $299/mo)
SkyRx has higher ratings (4.4/5 vs 4.3/5)
Sequence scores better on value (4.4/5 vs 3.6/5)
Sequence
$99/mo
starting price
Specializes in getting brand-name GLP-1s covered by insurance. They handle prior authorization so you don't have to.
SkyRx
$299/mo
starting price
Premium GLP-1 program with full labs, high-touch clinician access, and both semaglutide and tirzepatide.
Sequence vs SkyRx: Full Comparison
| Sequence | SkyRx | |
|---|---|---|
| ClearScore | 79/100 ✓ | 75/100 |
| Overall Rating | 4.3/5 | 4.4/5 ✓ |
| Review Count | 96 ✓ | 58 |
| Starting Price | $99/mo ✓ | $299/mo |
| Medications | Branded Wegovy, Branded Zepbound, Branded Mounjaro, Branded Ozempic ✓ | Compounded Semaglutide, Compounded Tirzepatide |
| Telehealth | Yes | Yes |
| Insurance | Accepted | Not accepted |
| HSA/FSA | Accepted | Accepted |
| Founded | 2021 | 2022 |
| States Served | All 50 states | All 50 states |
Programs & Pricing
Sequence Programs
Insurance-Covered GLP-1
$99/mo + insurance copay
Medications: Branded Wegovy, Branded Zepbound, Branded Mounjaro, Branded Ozempic
- Insurance Navigation
- Prior Authorization
- Clinician Support
- Prescription Management
SkyRx Programs
Premium Weight Loss
$299/mo
Medications: Compounded Semaglutide, Compounded Tirzepatide
- Medication
- Full Labs
- Dedicated Clinician
- Priority Support
Ratings Breakdown
| Category | Sequence | SkyRx |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
Sequence edges out SkyRx with a ClearScore of 79 vs 75. Sequence is more affordable starting at $99/mo compared to $299/mo. For customer support, SkyRx rates higher (4.8/5). The best choice depends on your priorities, medication preferences, and budget.