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Mayo Clinic Diet vs Physicians Weight Loss Centers: Prices, Programs & Reviews (2026)

Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.

Quick answer

Mayo Clinic Diet starts at $50/mo and Physicians Weight Loss Centers at $299/mo. Mayo Clinic Diet scores higher on our ClearScore (78 vs 72), and Mayo Clinic Diet is the cheaper starting option.

Quick Verdict

Mayo Clinic Diet has the higher ClearScore (78 vs 72)

Mayo Clinic Diet is more affordable ($50/mo vs $299/mo)

Mayo Clinic Diet has higher ratings (4.4/5 vs 4.1/5)

Bar chart comparing Mayo Clinic Diet vs Physicians Weight Loss Centers: ClearScore, price, and ratings
Mayo Clinic Diet logo

Mayo Clinic Diet

78
Very Good

$50/mo

starting price

World-renowned Mayo Clinic's evidence-based weight loss program now includes GLP-1 prescribing with specialized meal plans for medication users.

World-Class ReputationEvidence-BasedGLP-1 Meal Plans
Visit Mayo Clinic Diet
Physicians Weight Loss Centers logo

Physicians Weight Loss Centers

72
Good

$299/mo

starting price

National franchise with clinics across the East Coast offering physician-supervised GLP-1 programs with weekly check-ins and meal plans.

East CoastWeekly Check-InsMeal Plans
Visit Physicians Weight Loss Centers

Mayo Clinic Diet vs Physicians Weight Loss Centers: Full Comparison

Mayo Clinic Diet Physicians Weight Loss Centers
ClearScore 78/100 72/100
Overall Rating 4.4/5 4.1/5
Review Count 98 189
Starting Price $50/mo $299/mo
Medications Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide Branded Semaglutide, Branded Tirzepatide
Telehealth Yes No
Insurance Not accepted Accepted
HSA/FSA Accepted Accepted
Founded 1889 1986
States Served All 50 states 12 states

Programs & Pricing

Mayo Clinic Diet Programs

Companion Subscription

$49.99/mo (diet support only)

  • Mayo Clinic Diet Program
  • Glp1 Meal Plan
  • Nutrition Guidance

Clinical Subscription

$99.99/mo + $99.99 start fee + medication

Medications: Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide

  • Clinician Visits Via Amwell
  • Mayo Clinic Diet Program
  • Glp1 Meal Plan
  • Nutrition Guidance
  • Exercise Program
View All Mayo Clinic Diet Plans

Physicians Weight Loss Centers Programs

GLP-1 Weight Loss Program

$299/mo

Medications: Branded Semaglutide, Branded Tirzepatide

  • Medication
  • Weekly Check Ins
  • Body Composition
  • Personalized Meal Plan
View All Physicians Weight Loss Centers Plans

Ratings Breakdown

Category Mayo Clinic Diet Physicians Weight Loss Centers
Overall
4.4
4.1
Value
3.8
3.8
Ease of Use
4.2
3.9
Support
4.3
4.3
Medication Quality
4.7
4.4
Results
4.5
4.2

The Bottom Line

Mayo Clinic Diet edges out Physicians Weight Loss Centers with a ClearScore of 78 vs 72. Mayo Clinic Diet is more affordable starting at $50/mo compared to $299/mo. The best choice depends on your priorities, medication preferences, and budget.

Frequently Asked Questions

Is Mayo Clinic Diet or Physicians Weight Loss Centers cheaper?
Mayo Clinic Diet starts at a lower price point ($50/mo vs $299/mo). However, pricing depends on the specific program and medication you choose, so compare each provider's program details carefully.
Which provider has better reviews, Mayo Clinic Diet or Physicians Weight Loss Centers?
Mayo Clinic Diet has a higher overall rating (4.4/5 vs 4.1/5). Mayo Clinic Diet has 98 reviews and Physicians Weight Loss Centers has 189 reviews. Both ratings and review volume matter when evaluating providers.
Do Mayo Clinic Diet and Physicians Weight Loss Centers offer the same medications?
Mayo Clinic Diet offers Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide. Physicians Weight Loss Centers offers Branded Semaglutide, Branded Tirzepatide. Your prescriber will recommend the best medication based on your health profile, weight loss goals, and medical history.
Can I use insurance with Mayo Clinic Diet or Physicians Weight Loss Centers?
Mayo Clinic Diet does not currently accept insurance. Physicians Weight Loss Centers accepts insurance. For out-of-pocket costs, both providers accept HSA/FSA cards.

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