Sesame vs Yucca Health: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
Quick Verdict
Sesame has the higher ClearScore (74 vs 72)
Sesame is more affordable ($99/mo vs $146/mo)
Yucca Health has higher ratings (4.6/5 vs 4.1/5)
Yucca Health scores better on value (4.6/5 vs 4.3/5)
Sesame
$99/mo
starting price
Wide medication selection with 14 options, insurance navigation support, and same-day consultations starting at $99/month.
Yucca Health
$146/mo
starting price
Compounded GLP-1s from $146/mo. 50-state telehealth, 2-day shipping, 20K+ patients, LegitScript verified.
Sesame vs Yucca Health: Full Comparison
| Sesame | Yucca Health | |
|---|---|---|
| ClearScore | 74/100 ✓ | 72/100 |
| Overall Rating | 4.1/5 | 4.6/5 ✓ |
| Review Count | 156 | 20,000 ✓ |
| Starting Price | $99/mo ✓ | $146/mo |
| Medications | Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide, Metformin, Contrave ✓ | Compounded Semaglutide, Compounded Tirzepatide |
| Telehealth | Yes | Yes |
| Insurance | Accepted | Not accepted |
| HSA/FSA | Accepted | Not accepted |
| Founded | 2018 | 2023 |
| States Served | All 50 states | All 50 states |
Programs & Pricing
Sesame Programs
Success by Sesame
$99/mo + medication
Medications: Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide
- Clinician Consultations
- Labs Included
- Insurance Navigation
- Same Day Appointments
Yucca Health Programs
Semaglutide Program
From $146/mo (6-month plan)
Medications: Compounded Semaglutide
- Medication
- Consultation
- Supplies
- Shipping
Tirzepatide Program
From $258/mo (6-month plan)
Medications: Compounded Tirzepatide
- Medication
- Consultation
- Supplies
- Shipping
Ratings Breakdown
| Category | Sesame | Yucca Health |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
Sesame edges out Yucca Health with a ClearScore of 74 vs 72. Sesame is more affordable starting at $99/mo compared to $146/mo. For customer support, Yucca Health rates higher (4.5/5). The best choice depends on your priorities, medication preferences, and budget.