GLP-1 Care in Sioux Falls, SD: Local and Online Options

Start with the local directory if you want an in-person appointment. The online providers below are listed as serving South Dakota; that does not mean they have a clinic in Sioux Falls. This is not a complete list or a clinical ranking. Confirm your address, current services and prescription eligibility directly.

In-person care in Sioux Falls

Check each clinic's actual address, current weight-management services, appointment availability and consultation fee. A directory listing does not confirm GLP-1 prescribing.

Browse the Sioux Falls clinic directory

Two Sioux Falls services to contact before choosing online care

Official pages checked September 16, 2026. This is an AI-assisted public-source comparison, not a clinical ranking. We did not book appointments or verify individual eligibility, clinician credentials or insurance benefits.

Sanford Weight Management Center

3401 W 49th Street, Sioux Falls, SD 57106. 605-328-8670. The official location page describes adult surgical and nonsurgical weight-management care, plus a separate pediatric program. Do not interpret pediatric program eligibility as eligibility for any particular drug.

Ask for an adult nonsurgical appointment if that is your goal, whether a referral is required, and which medication evaluations are available. The checked page does not provide an all-in GLP-1 price or confirm your prescription coverage.

Avera Comprehensive Weight Management, 41st & Holbrook

6000 W 41st Street, Suite 100, Sioux Falls, SD 57106. 605-504-0400. Its official location page lists weight-management clinicians, counseling and clinical pharmacology. Posted hours are Monday through Thursday 7:30am to 5:30pm and Friday 7:30am to 1pm. Confirm before travelling.

The page includes a Medicare GLP-1 Bridge Program heading. That heading alone does not establish enrollment, covered products or your eligibility. Ask the clinic and your plan for current requirements rather than assuming all Medicare patients qualify.

Compare the appointment and the prescription separately

For either service, request the consultation fee, follow-up schedule, lab costs and expected medication charge. Ask who handles prior authorization and what happens if coverage is denied. Neither checked source supports a cheapest-provider claim. An online provider listed below is not necessarily a local clinic or an in-network alternative.

These are direct, non-affiliate source links. Current appointments, treatment choices and total costs remain subject to confirmation.

Online providers listed for South Dakota

Alphabetical order, not a best-to-worst ranking. Listed prices can depend on dose, pharmacy, eligibility and prepayment. Confirm the full initial charge and renewal terms.

Big Easy Weight Loss

Telehealth