Calibrate vs Fifty 410: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
Quick Verdict
Calibrate has the higher ClearScore (76 vs 68)
Fifty 410 is more affordable ($166/mo vs $199/mo)
Fifty 410 has higher ratings (4.5/5 vs 4.3/5)
Fifty 410 scores better on value (4.3/5 vs 3.8/5)
Calibrate
$199/mo
starting price
Year-long metabolic reset with dedicated coaching, GLP-1 medication, and a structured curriculum covering all lifestyle factors.
Fifty 410
$166/mo
starting price
Multi-month discounts on tirzepatide. 4.9 Trustpilot rating (2,847 reviews). Uses 503A and 503B pharmacies.
Calibrate vs Fifty 410: Full Comparison
| Calibrate | Fifty 410 | |
|---|---|---|
| ClearScore | 76/100 ✓ | 68/100 |
| Overall Rating | 4.3/5 | 4.5/5 ✓ |
| Review Count | 74 | 2,847 ✓ |
| Starting Price | $199/mo | $166/mo ✓ |
| Medications | Compounded Semaglutide, Compounded Tirzepatide | Compounded Semaglutide, Compounded Tirzepatide |
| Telehealth | Yes | Yes |
| Insurance | Not accepted | Not accepted |
| HSA/FSA | Accepted | Accepted |
| Founded | 2020 | 2023 |
| States Served | All 50 states | All 50 states |
Programs & Pricing
Calibrate Programs
Metabolic Reset
$199/mo
Medications: Compounded Semaglutide, Compounded Tirzepatide
- Medication
- Dedicated Coach
- Metabolic Curriculum
- Lab Work
Fifty 410 Programs
Semaglutide (4 weeks)
$199/mo
Medications: Compounded Semaglutide
- Medication
- Clinician Support
- Free Shipping
Tirzepatide (4 weeks)
$299/mo
Medications: Compounded Tirzepatide
- Medication
- Clinician Support
- Free Shipping
Tirzepatide (3-month plan)
From $166/mo
Medications: Compounded Tirzepatide
- Medication
- Clinician Support
- Free Shipping
Ratings Breakdown
| Category | Calibrate | Fifty 410 |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
Calibrate edges out Fifty 410 with a ClearScore of 76 vs 68. Fifty 410 is more affordable starting at $166/mo compared to $199/mo. For customer support, Calibrate rates higher (4.7/5). The best choice depends on your priorities, medication preferences, and budget.