Fifty 410 vs PlushCare: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
Quick Verdict
PlushCare has the higher ClearScore (70 vs 68)
PlushCare is more affordable ($20/mo vs $166/mo)
Fifty 410 has higher ratings (4.5/5 vs 4/5)
Fifty 410 scores better on value (4.3/5 vs 3.8/5)
Fifty 410
$166/mo
starting price
Multi-month discounts on tirzepatide. 4.9 Trustpilot rating (2,847 reviews). Uses 503A and 503B pharmacies.
PlushCare
$20/mo
starting price
Full-service virtual primary care with board-certified doctors prescribing brand-name GLP-1s and insurance billing.
Fifty 410 vs PlushCare: Full Comparison
| Fifty 410 | PlushCare | |
|---|---|---|
| ClearScore | 68/100 | 70/100 ✓ |
| Overall Rating | 4.5/5 ✓ | 4/5 |
| Review Count | 2,847 ✓ | 174 |
| Starting Price | $166/mo | $20/mo ✓ |
| Medications | Compounded Semaglutide, Compounded Tirzepatide | Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide, Contrave ✓ |
| Telehealth | Yes | Yes |
| Insurance | Not accepted | Accepted |
| HSA/FSA | Accepted | Accepted |
| Founded | 2023 | 2014 |
| States Served | All 50 states | All 50 states |
Programs & Pricing
Fifty 410 Programs
Semaglutide (4 weeks)
$199/mo
Medications: Compounded Semaglutide
- Medication
- Clinician Support
- Free Shipping
Tirzepatide (4 weeks)
$299/mo
Medications: Compounded Tirzepatide
- Medication
- Clinician Support
- Free Shipping
Tirzepatide (3-month plan)
From $166/mo
Medications: Compounded Tirzepatide
- Medication
- Clinician Support
- Free Shipping
PlushCare Programs
Weight Loss Program
$19.99/mo + consults + medication
Medications: Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide
- Membership Access
- Prescription Discount Card
- Provider Messaging
Ratings Breakdown
| Category | Fifty 410 | PlushCare |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
PlushCare edges out Fifty 410 with a ClearScore of 70 vs 68. PlushCare is more affordable starting at $20/mo compared to $166/mo. For customer support, Fifty 410 rates higher (4.5/5). The best choice depends on your priorities, medication preferences, and budget.