LifeMD vs Sesame: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
LifeMD starts at $199/mo and Sesame at $99/mo. LifeMD scores higher on our ClearScore (76 vs 74), and Sesame is the cheaper starting option.
Quick Verdict
LifeMD has the higher ClearScore (76 vs 74)
Sesame is more affordable ($99/mo vs $199/mo)
LifeMD has higher ratings (4.3/5 vs 4.1/5)
Sesame scores better on value (4.3/5 vs 4.2/5)
LifeMD
$199/mo
starting price
Board-certified doctors prescribing GLP-1s with both compounded and brand-name options. Known for responsive customer service.
Sesame
$99/mo
starting price
Wide medication selection with 14 options, insurance navigation support, and same-day consultations starting at $99/month.
LifeMD vs Sesame: Full Comparison
| LifeMD | Sesame | |
|---|---|---|
| ClearScore | 76/100 ✓ | 74/100 |
| Overall Rating | 4.3/5 ✓ | 4.1/5 |
| Review Count | 165 ✓ | 156 |
| Starting Price | $199/mo | $99/mo ✓ |
| Medications | Compounded Semaglutide, Compounded Tirzepatide | Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide, Metformin, Contrave ✓ |
| Telehealth | Yes | Yes |
| Insurance | Not accepted | Accepted |
| HSA/FSA | Accepted | Accepted |
| Founded | 2020 | 2018 |
| States Served | All 50 states | All 50 states |
Programs & Pricing
LifeMD Programs
GLP-1 Weight Management
$199/mo
Medications: Compounded Semaglutide, Compounded Tirzepatide
- Medication
- Board Certified Doctor
- Ongoing Monitoring
- Free Shipping
Sesame Programs
Success by Sesame
$99/mo + medication
Medications: Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide
- Clinician Consultations
- Labs Included
- Insurance Navigation
- Same Day Appointments
Ratings Breakdown
| Category | LifeMD | Sesame |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
LifeMD edges out Sesame with a ClearScore of 76 vs 74. Sesame is more affordable starting at $99/mo compared to $199/mo. For customer support, LifeMD rates higher (4.6/5). The best choice depends on your priorities, medication preferences, and budget.