PlushCare vs Sesame: Prices, Programs & Reviews (2026)
Side-by-side comparison updated for 2026. ClearScores, pricing, medications, and ratings compared.
PlushCare starts at $20/mo and Sesame at $99/mo. Sesame scores higher on our ClearScore (70 vs 74), and PlushCare is the cheaper starting option.
Quick Verdict
Sesame has the higher ClearScore (74 vs 70)
PlushCare is more affordable ($20/mo vs $99/mo)
Sesame has higher ratings (4.1/5 vs 4/5)
Sesame scores better on value (4.3/5 vs 3.8/5)
PlushCare
$20/mo
starting price
Full-service virtual primary care with board-certified doctors prescribing brand-name GLP-1s and insurance billing.
Sesame
$99/mo
starting price
Wide medication selection with 14 options, insurance navigation support, and same-day consultations starting at $99/month.
PlushCare vs Sesame: Full Comparison
| PlushCare | Sesame | |
|---|---|---|
| ClearScore | 70/100 | 74/100 ✓ |
| Overall Rating | 4/5 | 4.1/5 ✓ |
| Review Count | 174 ✓ | 156 |
| Starting Price | $20/mo ✓ | $99/mo |
| Medications | Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide, Contrave | Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide, Metformin, Contrave ✓ |
| Telehealth | Yes | Yes |
| Insurance | Accepted | Accepted |
| HSA/FSA | Accepted | Accepted |
| Founded | 2014 | 2018 |
| States Served | All 50 states | All 50 states |
Programs & Pricing
PlushCare Programs
Weight Loss Program
$19.99/mo + consults + medication
Medications: Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide
- Membership Access
- Prescription Discount Card
- Provider Messaging
Sesame Programs
Success by Sesame
$99/mo + medication
Medications: Branded Semaglutide, Branded Tirzepatide, Branded Liraglutide
- Clinician Consultations
- Labs Included
- Insurance Navigation
- Same Day Appointments
Ratings Breakdown
| Category | PlushCare | Sesame |
|---|---|---|
| Overall | | |
| Value | | |
| Ease of Use | | |
| Support | | |
| Medication Quality | | |
| Results | | |
The Bottom Line
Sesame edges out PlushCare with a ClearScore of 74 vs 70. PlushCare is more affordable starting at $20/mo compared to $99/mo. For customer support, PlushCare rates higher (3.7/5). The best choice depends on your priorities, medication preferences, and budget.