Provider Review · Updated March 2026
Pomegranate Health Review 2026: Low-Cost GLP-1 With Vitamin-Enhanced Formulas
Pomegranate Health offers compounded semaglutide with B12 for $119/month and compounded tirzepatide with B6 for $179/month. They claim over 100,000 patients and work with five compounding pharmacies including BPI, Empower, and Hallandale. There is a $75 consultation fee, though it gets credited toward your first medication order. Not available in California, Iowa, or Wisconsin. Trustpilot reviews are mixed at 3.5/5 with 108 reviews. The pricing is among the lowest we track, but the trust signals are uneven.
Quick Facts
| Detail | Pomegranate Health |
|---|---|
| Monthly Cost | From $119/mo (semaglutide + B12) |
| Medications | Compounded semaglutide + B12, compounded tirzepatide + B6, Metformin, Contrave, Rybelsus |
| What’s Included | Provider consultation, prescription, medication, ongoing support |
| States Served | 47 states (NOT available in CA, IA, or WI) |
| Insurance | No (cash-pay only) |
| Trustpilot | 3.5/5 (108 reviews) |
| ClearScore | 60/100 |
What Is Pomegranate Health?
Pomegranate Health is a telehealth weight loss provider that prescribes compounded GLP-1 medications with added vitamins. Their semaglutide comes compounded with B12, and their tirzepatide is compounded with B6. The B6 addition in tirzepatide is worth noting because some research suggests B6 may help reduce nausea, which is the most common side effect of GLP-1 medications.
They claim over 100,000 patients, which would make them one of the larger providers in this space. That number is hard to verify independently, but their pharmacy network supports the scale claim. They work with BPI, Empower, Hallandale, Redrock, and OptioRx. Having five pharmacy partners means they can maintain supply even when individual pharmacies face shortages or regulatory issues.
Beyond GLP-1 medications, Pomegranate Health also prescribes Metformin, Contrave, and brand-name Rybelsus (oral semaglutide). This broader medication menu means they can offer alternatives if a patient is not a candidate for compounded injectables.
How It Works
- Pay the $75 consultation fee. This gets credited toward your first medication order, so it functions as a deposit.
- Complete a health assessment. You provide your medical history, weight, medications, and goals.
- Provider consultation. A licensed clinician reviews your information and determines the right medication and dose.
- Pharmacy selection. Pomegranate Health routes your prescription to one of their five pharmacy partners based on availability and your location.
- Medication ships. Your compounded semaglutide + B12 or tirzepatide + B6 is shipped to your address.
- Ongoing management. You stay connected with your provider for dose adjustments and refills.
The multi-pharmacy model is unusual. Most telehealth providers work with one or two pharmacies. Pomegranate Health’s five-pharmacy network (BPI, Empower, Hallandale, Redrock, OptioRx) means they can route around supply shortages and find the best pricing for each patient’s situation.
Pricing: What It Actually Costs
Pomegranate Health charges a $75 consultation fee upfront. This fee gets credited toward your first medication purchase, so it functions more like a deposit than an additional cost.
Medication Pricing
| Medication | Monthly Price |
|---|---|
| Semaglutide + B12 | $119/mo |
| Tirzepatide + B6 | $179/mo |
| Consultation Fee | $75 (credited toward first order) |
At $119/month, the semaglutide pricing is well below Hims ($199/month) and Ro ($149/month). It is competitive with IVY RX and close to the lowest prices we track.
Tirzepatide at $179/month is also competitive. The SURMOUNT-5 trial demonstrated 20.2% weight loss with tirzepatide versus 13.7% with semaglutide over 72 weeks (NEJM, 2025). At just $60/month more than their semaglutide, the tirzepatide upgrade is reasonably priced.
The $75 consultation fee is standard for this tier of provider. Some competitors waive it entirely. Others bake it into higher monthly pricing. Since it credits toward medication, the net impact is minimal.
For a full pricing comparison across providers, see our cheapest GLP-1 guide.
What’s Included
- Provider consultation ($75, credited toward first medication order)
- Prescription for compounded semaglutide + B12 or tirzepatide + B6
- Medication shipped to your door
- Ongoing clinical support
- Access to alternative medications (Metformin, Contrave, Rybelsus)
- Five pharmacy partners for supply reliability
The Vitamin Addition: Does B6 in Tirzepatide Help?
Pomegranate Health adds B6 (pyridoxine) to their compounded tirzepatide formulation. The reasoning is that B6 may help reduce GLP-1-related nausea, which affects roughly 20-30% of patients in clinical trials.
Some evidence supports this. B6 has been studied as an anti-nausea agent, particularly in pregnancy-related nausea. Whether it meaningfully reduces GLP-1 side effects has not been proven in large clinical trials specific to this context. But the addition is low-risk and may provide a real benefit for patients who are sensitive to nausea.
The semaglutide formulation includes B12, which is a common addition across many compounding providers. B12 supports energy levels and is generally well-tolerated.
The Alternative Medication Menu
Unlike most compounded GLP-1 providers that only offer semaglutide and tirzepatide, Pomegranate Health has a broader medication menu:
- Metformin: A well-established diabetes medication that can aid weight loss. Often prescribed alongside GLP-1 medications or as a starter for patients with lower BMIs.
- Contrave: A combination of naltrexone and bupropion that targets food cravings through the brain’s reward system. Works differently than GLP-1 medications and may be appropriate for patients who cannot tolerate injectables.
- Rybelsus: Brand-name oral semaglutide in tablet form. Unlike compounded versions, this is the FDA-approved product from Novo Nordisk. It is typically more expensive but offers the assurance of brand-name manufacturing.
This variety means Pomegranate Health can serve a wider range of patients. If you try compounded semaglutide and the side effects are too strong, they can pivot you to Metformin or Contrave without transferring to a new provider. That flexibility has real value.
Pros and Cons
What I Like
- Semaglutide at $119/month is among the lowest prices we track
- B6 in tirzepatide may help with nausea (a common side effect)
- Five pharmacy partners (BPI, Empower, Hallandale, Redrock, OptioRx) provide supply flexibility
- Also offers Metformin, Contrave, and brand-name Rybelsus as alternatives
What Could Be Better
- Not available in California, Iowa, or Wisconsin
- $75 consultation fee adds upfront cost (though it credits toward medication)
- Trustpilot score of 3.5/5 is below average for this space
- Mixed reviews mention inconsistent customer service and communication delays
Ready to explore Pomegranate Health?
Check Pomegranate Health Prices →How Pomegranate Health Compares
Pomegranate Health vs. Ro
Ro charges $149/month for compounded semaglutide with a stronger brand and more reviews. Pomegranate Health is $30/month cheaper and adds B12 to the formulation. Ro has better customer service ratings and a more established clinical team. See all Ro details.
Pomegranate Health vs. Hims
Hims charges $199/month for compounded semaglutide, which is $80/month more than Pomegranate Health. Hims has a larger platform with additional health services and a much stronger Trustpilot presence. Pomegranate Health wins on price and offers tirzepatide, which Hims also carries. See all Hims details.
Who Is Pomegranate Health Best For?
Pomegranate Health fits best for patients who:
- Want the lowest monthly price and are willing to trade brand recognition for savings
- Are concerned about nausea and want the B6-enhanced tirzepatide formulation
- Want medication flexibility and may need to try Metformin, Contrave, or Rybelsus as alternatives
- Value pharmacy network depth with five sourcing options for supply reliability
Pomegranate Health is probably not the right fit if you live in California, Iowa, or Wisconsin. It is also not ideal if consistent customer service is a top priority (given the 3.5 Trustpilot score) or if you prefer a provider with a stronger public reputation.
State Availability
Pomegranate Health is available in 47 states. The three states where they do NOT operate:
- California - likely due to California’s strict telehealth prescribing regulations
- Iowa - state-specific licensing or prescribing restrictions
- Wisconsin - similar regulatory constraints
If you live in one of these three states, check our provider directory to find alternatives that serve your location. Most major telehealth GLP-1 providers cover all 50 states, so you will have plenty of options.
The Bottom Line
Pomegranate Health is a budget-friendly option with a couple of genuine differentiators: vitamin-enhanced formulations and a deep pharmacy network. The $119/month semaglutide price is hard to beat, and the B6 addition in tirzepatide is a thoughtful touch for patients worried about nausea. If price is your top priority and you are not in California, Iowa, or Wisconsin, Pomegranate Health deserves a closer look.
The 3.5 Trustpilot score gives me pause though. Mixed customer service reviews and a below-average rating suggest inconsistency. If you want a provider with a stronger track record at a slightly higher price point, Ro or Henry Meds are safer picks. Browse all options in our provider directory.
FAQ
Is Pomegranate Health legitimate?
Pomegranate Health is a licensed telehealth provider operating in 47 states. They work with established compounding pharmacies including BPI and Empower. They claim 100,000+ patients. Trustpilot reviews are mixed at 3.5/5 with 108 reviews.
What states does Pomegranate Health not serve?
Pomegranate Health is not available in California, Iowa, or Wisconsin. They serve all other 47 states.
Why does Pomegranate Health add B6 to tirzepatide?
B6 (pyridoxine) may help reduce nausea, which is the most common side effect of GLP-1 medications. Some evidence supports B6 as an anti-nausea agent, though large-scale clinical trials specific to GLP-1 nausea have not been published.
How much does Pomegranate Health cost?
Semaglutide + B12 costs $119/month. Tirzepatide + B6 costs $179/month. There is a $75 consultation fee that gets credited toward your first medication order.
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