Provider Review · Updated March 2026
Fifty 410 Review 2026: The Best-Reviewed Compounding Provider We’ve Found
Fifty 410 offers compounded semaglutide starting at $199/month or $99/month on a 3-month plan. Compounded tirzepatide starts at $299/month or $166/month with a 3-month starter. What really stands out is their Trustpilot profile: 4.8 out of 5 stars across 4,179 reviews. That is the highest score and largest review volume of any compounding GLP-1 provider we track. They work with both 503A (ProRx) and 503B (BPI) pharmacies and accept Afterpay and Affirm for payment flexibility.
Quick Facts
| Detail | Fifty 410 |
|---|---|
| Monthly Cost | From $99/mo (3-month semaglutide plan) |
| Medications | Compounded semaglutide, compounded tirzepatide |
| What’s Included | Provider consultation, prescription, medication, ongoing support |
| States Served | All 50 US states |
| Insurance | No (cash-pay only, Afterpay/Affirm available) |
| Trustpilot | 4.8/5 (4,179 reviews) |
| ClearScore | 68/100 |
What Is Fifty 410?
Fifty 410 is a telehealth weight loss provider specializing in compounded GLP-1 medications. They offer both semaglutide and tirzepatide through licensed compounding pharmacies, with aggressive multi-month pricing that makes them one of the more affordable options in telehealth right now.
The company sources medications from ProRx (a 503A pharmacy) and BPI (a 503B outsourcing facility). Having a 503B pharmacy in the mix is notable because 503B facilities operate under stricter FDA oversight than standard 503A pharmacies. This matters given the ongoing scrutiny around compounded GLP-1 quality.
Their Trustpilot presence is their strongest trust signal. With 4,179 reviews and a 4.8 rating, they have more verified customer feedback than most providers in this space. For context, Hims has around 7,800 reviews but at a lower rating. Among compounding-only providers, Fifty 410 leads the pack.
The LegitScript certification is another positive. LegitScript verifies that telehealth pharmacies and providers meet regulatory standards, and not every compounding provider in this space has earned it. It does not guarantee a perfect experience, but it is one more data point in Fifty 410’s favor.
How It Works
Getting started with Fifty 410 follows a standard telehealth flow:
- Complete an online assessment. You answer questions about your medical history, current medications, weight loss goals, and any contraindications.
- Provider review. A licensed clinician reviews your information and determines if you are a candidate for GLP-1 medication.
- Choose your plan. Select month-to-month or a multi-month option for semaglutide or tirzepatide.
- Medication ships. Your compounded medication is prepared at ProRx or BPI and shipped directly to your address.
- Ongoing support. You have access to your care team for dosage adjustments, side effect management, and prescription renewals.
The process takes a few days from sign-up to receiving your medication. Some patients report faster turnaround, while others mention 5-7 business days depending on pharmacy workload.
Pricing: What It Actually Costs
Fifty 410 runs a discount-heavy pricing model. Month-to-month rates are middle-of-the-road, but the multi-month plans drop the price significantly.
Semaglutide Pricing
| Plan | Price |
|---|---|
| Month-to-Month | $199/mo |
| 3-Month Plan | $99/mo |
Tirzepatide Pricing
| Plan | Price |
|---|---|
| Month-to-Month | $299/mo |
| 3-Month Starter | $166/mo |
At $99/month for semaglutide, the 3-month plan undercuts almost every competitor we track. Hims charges $199/month. Ro starts at $149/month. Even budget providers like IVY RX at $175/month cannot match that number.
The tirzepatide pricing at $166/month on the starter plan is also competitive. In the SURMOUNT-5 trial, tirzepatide produced 20.2% weight loss versus 13.7% for semaglutide over 72 weeks (NEJM, 2025). At this price point, the upgrade to tirzepatide is worth considering.
No hidden fees. No contracts. You can cancel anytime, though multi-month plans are paid upfront.
For a full pricing comparison, see our cheapest GLP-1 guide.
What’s Included
- Licensed provider consultation
- Prescription for compounded semaglutide or tirzepatide
- Medication shipped to your door
- Ongoing clinical support
- No membership or platform fees
- Afterpay and Affirm financing available
- LegitScript certification
503A vs. 503B: Why the Pharmacy Type Matters
Fifty 410 works with both ProRx (a 503A pharmacy) and BPI (a 503B outsourcing facility). Understanding the difference matters when choosing a compounded GLP-1 provider.
503A pharmacies compound medications based on individual patient prescriptions. They are regulated by state pharmacy boards and typically serve local or regional patients. ProRx is a well-known 503A pharmacy in the GLP-1 space.
503B outsourcing facilities operate under direct FDA oversight. They can produce larger batches without patient-specific prescriptions and must follow Current Good Manufacturing Practice (cGMP) standards. BPI is one of the more established 503B facilities. The FDA-level oversight means tighter quality controls, batch testing, and manufacturing standards.
Having access to both pharmacy types gives Fifty 410 flexibility. If one pharmacy faces supply constraints or regulatory issues, they can route through the other. For patients, the BPI option offers an additional layer of quality assurance that not every telehealth provider can match.
For a deeper dive into how compounded GLP-1 medications differ from brand-name versions, read our compounded vs. brand-name GLP-1 guide.
Pros and Cons
What I Like
- Best Trustpilot score of any compounding-only provider (4.8/5, 4,179 reviews)
- Semaglutide at $99/month on the 3-month plan is among the lowest prices available
- Both 503A (ProRx) and 503B (BPI) pharmacies for sourcing flexibility
- No contracts, no membership fees
- Afterpay and Affirm for those who need to spread payments
What Could Be Better
- Multi-month plans require upfront payment, which locks you in before you know how you will respond to the medication
- Month-to-month pricing ($199 semaglutide, $299 tirzepatide) is not particularly competitive
- Limited information about their medical team on the website
- No clear refund policy published for multi-month plans if you need to stop treatment
Ready to explore Fifty 410?
Check Fifty 410 Prices →How Fifty 410 Compares
Fifty 410 vs. Ro
Ro charges $149/month for compounded semaglutide with a larger clinical infrastructure and pharmacy network. Fifty 410 beats them on price at $99/month (3-month plan) and has a stronger Trustpilot score. Ro offers more add-on services like metabolic testing. See all Ro details.
Fifty 410 vs. Hims
Hims offers compounded semaglutide at $199/month with the largest telehealth brand in the space. Fifty 410 is significantly cheaper on multi-month plans and has a higher Trustpilot rating (4.8 vs. Hims’ score). Hims has a larger product ecosystem if you want skincare, hair loss, or mental health bundled in. See all Hims details.
Who Is Fifty 410 Best For?
Fifty 410 fits best for patients who:
- Want the lowest possible monthly cost and are willing to pay upfront for a 3-month plan
- Value social proof and want a provider with thousands of verified reviews, not just a handful
- Care about pharmacy quality and want access to a 503B outsourcing facility
- Do not need extensive clinical support and are comfortable with a standard telehealth model
Fifty 410 is probably not the right fit if you want month-to-month flexibility without upfront commitment, need a provider with a large clinical team and extensive add-on services, or prefer a brand with a longer operational track record.
The Bottom Line
Fifty 410 is one of the strongest value picks in the compounded GLP-1 space. The combination of low multi-month pricing and a verified, high-volume Trustpilot score makes them a credible option for people prioritizing affordability and social proof. If you are comfortable committing to a 3-month plan upfront, the $99/month semaglutide price is hard to beat.
That said, if you prefer month-to-month flexibility or want a larger provider with more clinical infrastructure, Ro or Hims might be better fits. And if you are unsure which provider matches your needs, browse our full provider directory to compare options side by side.
FAQ
Is Fifty 410 legitimate?
Fifty 410 is a LegitScript-certified telehealth provider with 4,179 Trustpilot reviews at a 4.8 rating. They work with licensed 503A and 503B compounding pharmacies (ProRx and BPI). This is one of the more verifiable providers in the compounded GLP-1 space.
How much does Fifty 410 cost per month?
Compounded semaglutide costs $199/month or $99/month on a 3-month plan. Compounded tirzepatide costs $299/month or $166/month on a 3-month starter plan. No membership fees or consultation charges.
Does Fifty 410 accept insurance?
No. Fifty 410 is cash-pay only. They do accept Afterpay and Affirm for payment plans, and HSA/FSA cards may be accepted depending on your plan.
What pharmacies does Fifty 410 use?
Fifty 410 sources medications from ProRx (a 503A compounding pharmacy) and BPI (a 503B outsourcing facility). Having a 503B pharmacy is a positive sign, as these facilities operate under stricter FDA manufacturing standards.
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