Provider Review · Updated April 2026
Yucca Health Review 2026: Compounded GLP-1 With 2-Day Shipping
Yucca Health is a telehealth platform offering personalized compounded semaglutide from $146/month and compounded tirzepatide from $258/month on the 6-month plan. Medication is compounded by licensed U.S. pharmacies and shipped free with 2-day UPS. Board-certified providers are available in all 50 states, and intake is reviewed within 24 hours. Yucca also runs NAD+ and sermorelin programs for longevity and recovery. The platform is LegitScript verified, HIPAA compliant, and lists 20,000+ patients served.
Quick Facts
| Detail | Yucca Health |
|---|---|
| Compounded Semaglutide | From $146/mo (6-month plan, new patients) |
| Compounded Tirzepatide | From $258/mo (6-month plan, new patients) |
| Other Programs | NAD+ and sermorelin, $192/mo on 3-month plans |
| States Served | All 50 states |
| Insurance | Not accepted (cash pay, Klarna, Affirm, Afterpay available) |
| Shipping | Free 2-day UPS |
| Intake Review | Within 24 hours |
| Verification | LegitScript verified, HIPAA compliant |
| ClearScore | 72/100 |
Pricing
| Program | Plan Length | Starting Price |
|---|---|---|
| Compounded semaglutide | 6-month plan | From $146/mo |
| Compounded tirzepatide | 6-month plan | From $258/mo |
| NAD+ (longevity) | 3-month plan | $192/mo |
| Sermorelin (recovery) | 3-month plan | $192/mo |
Pricing is confirmed after intake once eligibility is verified. The entry prices quoted above apply to new patients on the 6-month GLP-1 plans. Monthly cost increases on shorter plans. Klarna, Affirm, and Afterpay are offered for split-payment setups.
On the semaglutide side, $146/mo sits near the low end of the market. For context, Hims charges $199/mo, Henry Meds is around $197/mo, and Novi starts at $174/mo. Tirzepatide at $258/mo is similarly competitive against Novi at $283/mo and MEDVi at $279/mo.
In the SURMOUNT-5 trial, tirzepatide produced 20.2% weight loss versus 13.7% for semaglutide over 72 weeks (NEJM, 2025). If you can afford the step up, the dual agonist has stronger trial data.
For the full pricing view, see our cheapest GLP-1 guide.
See Yucca's current pricing
Visit Yucca Health →How It Works
- Fill out an online questionnaire covering medical history, BMI, and weight goals
- Provider review within 24 hours by a board-certified physician licensed in your state
- Pharmacy compounding once eligibility is confirmed and the prescription is issued
- Free 2-day UPS delivery with injection supplies included
- Patient dashboard for tracking progress, messaging the provider, and adjusting treatment
Eligibility starts at BMI 30+, or BMI 27+ with weight-related conditions like type 2 diabetes, hypertension, or high cholesterol. Some patients with BMI 25+ may qualify based on medical history.
What I Like
Entry Price on Semaglutide
At $146/mo on the 6-month plan, Yucca is one of the cheaper compounded semaglutide programs on the market. That beats most mainstream telehealth platforms and lands close to bargain-tier options without dropping to the rock-bottom compounders that often lack clinical support.
24-Hour Intake Review
Some compounded GLP-1 platforms leave you waiting 3-5 days after submitting an intake. Yucca commits to a 24-hour review window. For anyone who has already decided to start, that speed matters.
Free 2-Day UPS Shipping
Expedited shipping is included on every order. A few competitors charge extra for 2-day delivery or ship USPS Ground. When you are managing a weekly injection schedule, faster shipping reduces the risk of a coverage gap between refills.
LegitScript and HIPAA Compliance
Yucca Health is LegitScript verified and HIPAA compliant. That does not guarantee clinical quality, but it filters out the grey-market pharmacies selling compounded peptides without proper oversight. For a compounded GLP-1 buyer, LegitScript is a basic floor I want to see.
Longevity and Recovery Add-Ons
Yucca also offers NAD+ and sermorelin through the same platform. If you are already thinking about muscle retention, recovery, or longevity stacking, having these under one provider is a convenience. Clinics selling sermorelin often charge more per month on short plans, so Yucca’s $192/mo 3-month pricing is fair.
What Could Be Better
6-Month Plan Commitment for Best Price
The advertised $146/mo for semaglutide requires a 6-month commitment. Shorter plans cost more per month. If you want to try GLP-1s without locking in for half a year, the effective price is higher than the headline number suggests.
Compounded Only, No Brand-Name Options
Yucca does not offer brand-name Wegovy, Ozempic, or Zepbound. If your insurance covers brand-name GLP-1s or you want FDA-approved drugs, look at Ro or Sesame instead.
Injections Only
All GLP-1 treatment is injectable. Yucca does not offer oral tablets, sublingual drops, or lozenges. Platforms like SHED or Synergy Rx offer multiple formats.
No Published Medical Director
Yucca’s website does not prominently name a medical director, CMO, or advisory board. For a compounded GLP-1 prescriber, I prefer to see the medical leadership publicly. The platform does list board-certified physicians in all 50 states, which is table stakes for telehealth.
No Insurance Coverage
Everything is cash pay. Klarna, Affirm, and Afterpay can split payments, but Yucca does not handle insurance prior authorization. If you want help getting Wegovy or Zepbound covered by insurance, Ro runs a concierge service for that.
Who Yucca Health Is Best For
Yucca could work if you:
- Want low-priced compounded semaglutide and are comfortable with a 6-month plan
- Value fast intake turnaround and free 2-day shipping
- Are fine with injectable GLP-1 only
- Are not looking for insurance coverage or brand-name medications
- Want the option to add NAD+ or sermorelin through the same provider
If you need brand-name Wegovy or Zepbound with insurance navigation, Ro is the better fit. If you want oral options, SHED or Synergy Rx are worth comparing.
Ready to check Yucca?
Visit Yucca Health →FAQ
Is Yucca Health legitimate?
Yucca Health is LegitScript verified and HIPAA compliant. Medication is compounded by licensed U.S. pharmacies and prescribed by board-certified physicians licensed in all 50 states. The platform reports 20,000+ patients served with a 4.8/5.0 rating across review platforms.
How much does Yucca Health cost?
Compounded semaglutide starts at $146/month for new patients on the 6-month plan. Compounded tirzepatide starts at $258/month on the 6-month plan. NAD+ and sermorelin are $192/month on 3-month plans. Shorter plans cost more per month. Klarna, Affirm, and Afterpay split-pay are accepted.
Does Yucca Health accept insurance?
No. All plans are cash pay. Klarna, Affirm, and Afterpay are available for payment splitting. Yucca does not handle insurance prior authorization for brand-name GLP-1 medications.
What medications does Yucca Health prescribe?
Compounded semaglutide, compounded tirzepatide, NAD+, and sermorelin. Yucca does not offer brand-name Wegovy, Ozempic, or Zepbound. GLP-1 treatments are injectable only.
How fast does Yucca ship?
Free 2-day UPS shipping on all orders. Intake questionnaires are reviewed within 24 hours by a licensed provider, and medication ships once the prescription is compounded.
Related
Guides:
Provider Reviews: Hims Review · Novi Review · Henry Meds Review · Ro Review · MEDVi Review
Compare: All Providers · Best GLP-1 Programs 2026