Provider Review · Updated November 2026
Pomegranate Health Review 2026: Low-Cost Compounded GLP-1s
Pomegranate Health sells compounded semaglutide from $129/month and compounded tirzepatide with B6 from $159/month, as of Nov 4, 2026. Both showed "Sold Out" on its app pricing page that day. It has no membership fee and does not require insurance. Trustpilot showed 4.0 out of 5 from 223 reviews on Nov 4, 2026.
Quick Facts
| Detail | Pomegranate Health |
|---|---|
| Compounded semaglutide | Starts at $129/mo (as of Nov 4, 2026) |
| Compounded tirzepatide + B6 | Starts at $159/mo (as of Nov 4, 2026) |
| Availability | Both shown as “Sold Out” on the app pricing page, Nov 4, 2026 |
| Other medications | Metformin, Contrave, Rybelsus, Foundayo, plus longevity injections |
| What’s included | Provider review, medication and delivery, per the product pages |
| Membership | None required |
| Insurance | Not required for compounded plans. FSA/HSA accepted per the homepage |
| Trustpilot | 4.0/5 from 223 reviews (checked Nov 4, 2026) |
What Is Pomegranate Health?
Pomegranate Health is a cash-pay telehealth provider that prescribes compounded GLP-1 medications along with other weight loss, skin, hair and longevity treatments. Its app pricing page lists its tirzepatide as “Tirzepatide + Pyridoxine (B6).”
The site says compounded medications are prepared by state-licensed pharmacies and have not been evaluated or approved by the FDA. In March 2026 the FDA warned 30 telehealth companies over marketing that implied compounded GLP-1s are the same as approved drugs. Pomegranate’s product pages also use the line “Direct from FDA-licensed manufacturer,” which can read as if the drug itself is FDA-approved. It is not.
The site lists “100,000+ patients” in one banner and “350,000+ patients” on the homepage. We could not verify either number.
Beyond GLP-1s, the app pricing page lists metformin, Contrave and Rybelsus “as low as $0 copay,” and the site also lists Foundayo (orforglipron). That gives you options if compounded injectables are not right for you.
How It Works
- Complete a health assessment with your history, weight and current medications.
- Provider review. A licensed clinician reviews your information. The app pricing page says patients new to GLP-1s need a BMI of 27 or higher with a related condition, or 30 or higher without one.
- Prescription. If approved, the prescription goes to a partner pharmacy.
- Medication ships to your address. The pricing page notes extra shipping charges may apply for Alaska, Puerto Rico and Hawaii.
- Ongoing management for dose changes and refills.
Follow your prescriber’s titration plan and do not change doses on your own. GLP-1 drugs carry a boxed warning about thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid cancer or MEN 2. Tell your clinician about severe stomach pain, which can signal pancreatitis, and about pregnancy plans.
Pricing: What It Actually Costs
| Medication | Price (as of Nov 4, 2026) |
|---|---|
| Compounded semaglutide | Starts at $129/mo |
| Compounded tirzepatide + B6 | Starts at $159/mo |
| Metformin, Contrave, Rybelsus | ”As low as $0 copay” with insurance |
The semaglutide page lists “Starts @ $129/mo” and says one price covers care, medication and shipping. The tirzepatide page lists “Starts @ $159/mo.” “Starts at” usually means the starting dose. Ask what you will pay at higher doses before you commit.
On Nov 4, 2026, the app pricing page showed both compounded products as “Sold Out,” with a note that “BPI is currently sold out.” Check availability before you sign up.
The SURMOUNT-5 trial (NEJM, 2025) found 20.2% weight loss with brand-name tirzepatide versus 13.7% with brand-name semaglutide over 72 weeks. Compounded versions were not tested in that trial.
For a full pricing comparison across providers, see our cheapest GLP-1 guide.
The B6 Addition: Does It Help?
Pomegranate adds B6 (pyridoxine) to its compounded tirzepatide. The idea is that B6 may ease nausea, a common GLP-1 side effect. B6 is used for nausea in pregnancy, but we found no clinical trial showing that adding B6 to tirzepatide reduces GLP-1 nausea. Treat it as unproven. If nausea is a problem, talk to your prescriber about dose timing or a slower titration.
The Alternative Medication Menu
- Metformin: A long-used diabetes drug that can modestly help weight loss in some patients.
- Contrave: Naltrexone and bupropion, which work on cravings through the brain’s reward system.
- Rybelsus: Brand-name oral semaglutide from Novo Nordisk, FDA-approved for type 2 diabetes.
If compounded injectables are sold out or not a fit, these give you a path without changing providers.
Pros and Cons
What I Like
- Semaglutide from $129/month is among the lower prices we track
- No membership fee
- Brand-name and generic alternatives on the same platform
- Trustpilot score of 4.0/5 from 223 reviews
What Could Be Better
- Both compounded GLP-1s showed “Sold Out” on Nov 4, 2026
- “Starts at” prices may rise with dose
- “Direct from FDA-licensed manufacturer” wording on compounded product pages can mislead
- Patient counts on the site conflict (100,000+ and 350,000+)
Ready to explore Pomegranate Health?
Check Pomegranate Health Prices →How Pomegranate Health Compares
Pomegranate Health vs. Ro
Ro charges $149/month for membership plus medication billed separately, per its weight loss page on Nov 4, 2026. Ro focuses on brand-name drugs. Pomegranate is cheaper on paper but sells compounded drugs.
Pomegranate Health vs. Hims
Hims did not show a public GLP-1 price on Nov 4, 2026. Hims has a larger platform with more health services.
Who Is Pomegranate Health Best For?
- Price-focused patients comfortable with compounded medication
- People who want options, such as metformin, Contrave or Rybelsus, on one platform
It is not the right fit if you want FDA-approved GLP-1 injections, or if you need to start right away while its compounded products are sold out.
The Bottom Line
Pomegranate Health has low list prices and a broad medication menu. On Nov 4, 2026, its compounded semaglutide and tirzepatide were both marked sold out in its app, so confirm availability first. Ask what you will pay at your maintenance dose. Browse all options in our provider directory.
Looking for an alternative?
Yucca Health described compounded semaglutide plans from $125 per month on a 6-month plan and $146 month-to-month on its semaglutide page as of Nov 4, 2026. Its pages show varying promo prices, so confirm at checkout.
Check Yucca Health Pricing →This direct provider link does not affect the review above.
FAQ
Is Pomegranate Health legitimate?
Pomegranate Health runs a working telehealth service with clinician review and partner pharmacies. It holds a 4.0/5 Trustpilot score from 223 reviews as of Nov 4, 2026. We could not verify its patient counts or the list of states it serves.
Is Pomegranate Health in stock?
On Nov 4, 2026, its app pricing page showed compounded semaglutide and tirzepatide as “Sold Out.” Check before you sign up.
Why does Pomegranate Health add B6 to tirzepatide?
B6 (pyridoxine) is meant to ease nausea. We found no clinical trial showing it reduces GLP-1 nausea, so treat it as unproven.
How much does Pomegranate Health cost?
As of Nov 4, 2026, compounded semaglutide starts at $129/month and compounded tirzepatide with B6 starts at $159/month. No membership is required.
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What we checked
This AI-assisted public-source desk check reviewed Pomegranate Health’s homepage, semaglutide and tirzepatide product pages and app pricing page, its Trustpilot profile, the SURMOUNT-5 trial record, an FDA press release on compounded GLP-1 marketing, and the Ro and Yucca pricing pages on November 4, 2026. We did not complete signup, pay for treatment, test delivery or support, or independently verify clinician and pharmacy credentials. Prices and policies change, so confirm them with the provider or your prescriber before you act.