Provider Review · Updated November 2026
SkyRx Review 2026: Compounded Semaglutide From $199/Month
SkyRx sells compounded semaglutide as a weekly injection or as oral drops, starting at $199/month when you prepay a 12-month plan. Tirzepatide is listed as coming soon. The SkyRx homepage leads with ED and NAD+ products, and the weight loss offer lives on a separate page. Here is what the site says, and what it leaves out.
Quick Facts
| Detail | SkyRx Weight Loss |
|---|---|
| Starting Price | From $199/mo with a 12-month subscription paid upfront (as of Nov 4, 2026) |
| Medications | Compounded semaglutide injection or oral drops. Tirzepatide listed as “coming soon” |
| What’s Included | Medication, supplies, doctor visit and shipping |
| Labs | Not mentioned on the weight loss page |
| States Served | Not all 50 states, per SkyRx. No state list published |
| Insurance | Not required or used |
| Address listed | Draper, UT |
What Is SkyRx?
SkyRx is a telehealth brand that sells prescription products online. On November 4, 2026, the SkyRx homepage listed erectile dysfunction treatments, women’s sexual health, oral ED strips, and NAD+ injections and nasal spray. It did not list or link a weight loss product.
The weight loss offer sits on a separate SkyRx weight loss page. That page sells compounded semaglutide injection and compounded semaglutide oral drops, and shows tirzepatide injection and oral drops as “coming soon.” Both pages list the same contact address in Draper, Utah.
So two things are true at once. SkyRx does still sell compounded semaglutide, but weight loss is not what the company puts first.
Pricing
According to the SkyRx weight loss page on Nov 4, 2026:
- Semaglutide injection “starts at $199/mo”
- Semaglutide oral drops “starts at $199/mo”
- The footnote says the $199/mo price requires “a 12-mo subscription. Pay upfront in full.”
- The FAQ says the price “includes medication, supplies, doctor visit and shipping.”
The page did not show a month-to-month price or a price for shorter plans. It says the actual price “will depend on product and subscription plan purchase.” Paying upfront for 12 months at $199/mo works out to $2,388 before any changes in dose or plan. That is our arithmetic, so confirm the checkout total before you pay.
A 12-month prepayment is a large commitment for a medication you have not tried yet. Ask SkyRx in writing what happens to the unused balance if you stop early or a clinician decides the drug is not right for you.
For a price comparison across providers, check our cheapest GLP-1 guide.
See SkyRx's current pricing
Visit SkyRx →What the Site Says About Care
- Clinician review: The FAQ says your doctor “is expected to review your chart within 24 hrs and often less than 5 hrs.”
- Prescribers: SkyRx says its providers are vetted and licensed to prescribe GLP-1 medications in your state.
- Labs: The weight loss page does not mention lab testing.
- Dedicated clinician: The page does not promise a dedicated clinician.
- Coaching: None described.
If ongoing lab monitoring or a single named clinician matters to you, ask SkyRx before you sign up, because the public page does not commit to either.
What Could Be Better
Weight Loss Is Not the Main Focus
The homepage does not link the weight loss page. That suggests GLP-1s are a side line for SkyRx, and it is harder to judge how much support you will get.
Tirzepatide Is Not Available Yet
Both tirzepatide products are listed as “coming soon.” If you want tirzepatide, you need another provider today. In the SURMOUNT-5 trial, tirzepatide produced 20.2% weight loss versus 13.7% for semaglutide at 72 weeks. See our Mounjaro vs Ozempic comparison for the clinical breakdown.
Not Available in Every State
The FAQ says GLP-1s “are not yet available in all 50 states.” SkyRx does not publish the list, so check your state during intake.
Compounded Medication Only
SkyRx’s own page says “Compounded semaglutide, is not approved or evaluated for safety, efficacy, or quality by FDA.” The FDA resolved the semaglutide injection shortage on February 21, 2025, which ended the shortage-based allowance for mass compounding. On February 6, 2026, the FDA said companies cannot claim compounded products are the same as FDA-approved drugs.
Oral drops are not the same product as the FDA-approved Wegovy pill. No large trial has tested compounded semaglutide drops. If you want an FDA-approved option, Ro prescribes brand-name medications only.
Little Public Track Record
We could not find enough third-party reviews of SkyRx’s weight loss program to judge reliability, support or delivery.
SkyRx NAD+ Products
SkyRx also lists NAD+ injections and NAD+ nasal spray on its homepage. These are separate from the weight loss program. We did not review the evidence for NAD+ products, and they are not a treatment for GLP-1 side effects. Talk to your prescriber before adding any product to a GLP-1 plan.
Who SkyRx Is Best For
SkyRx may fit if you:
- Want compounded semaglutide, either as an injection or oral drops
- Are comfortable prepaying 12 months to get the $199/mo price
- Do not need tirzepatide, lab monitoring, or coaching
SkyRx is not the best fit if you want tirzepatide today, want brand-name medication (Ro), want coaching (Found or Calibrate), or want a provider with a longer public track record.
Compare SkyRx with other providers
Browse All Providers →The Bottom Line
SkyRx sells compounded semaglutide at a low headline price, but only with a 12-month upfront payment. The weight loss page is short on detail about labs, clinician continuity and state coverage, and the homepage does not even link it. If you choose SkyRx, get the refund terms in writing first. Compare options in our provider directory or see the best GLP-1 programs for 2026.
FAQ
How much does SkyRx cost?
SkyRx lists compounded semaglutide injection and oral drops from $199/month with a 12-month subscription paid upfront (as of Nov 4, 2026). The price includes medication, supplies, a doctor visit and shipping. No month-to-month price was shown.
What medications does SkyRx offer?
Compounded semaglutide as an injection or oral drops. Tirzepatide injection and oral drops are listed as “coming soon.” SkyRx does not list brand-name medications such as Wegovy, Ozempic, Zepbound or Mounjaro.
Does SkyRx accept insurance?
SkyRx says it does not require insurance. It is a cash-pay program.
Is SkyRx available in my state?
SkyRx says GLP-1s are not yet available in all 50 states and does not publish a list. Check during intake.
Related
Guides:
- Cheapest Way to Get GLP-1 Online (2026)
- GLP-1 Side Effects Month by Month
- How to Get Insurance to Cover GLP-1 Meds
- Compounded vs Brand-Name GLP-1
Provider Reviews: MEDVi Review · Enhance MD Review · Hone Health Review · Henry Meds Review · Ro Review
Compare: All Providers · Best GLP-1 Programs 2026
What we checked
This AI-assisted public-source desk check reviewed the SkyRx homepage and weight loss page, the FDA’s compounding update and February 2026 statement, and the published SURMOUNT-5 trial on November 4, 2026. We did not complete signup, pay for treatment, test delivery or support, or independently verify clinician and pharmacy credentials. Prices and policies change, so confirm them with the provider or your prescriber before you act.